Principal Investigator – Clinical Trials (Phase III / IV) | RN
AC Group | Full-Time or Part-Time
About the Role
AC Group partners with leading pharmaceutical and biotech companies to conduct Phase III and Phase IV post-marketing clinical trials. We are actively seeking experienced Registered Nurses to serve as Principal Investigators within our research network. In Phase III and IV studies, an RN PI is fully qualified to lead site-level operations, hold regulatory accountability, and drive protocol execution — and we are built to support you in doing exactly that.
This is a compensated, flexible engagement with FMV-based pay structured around hourly rates, per-patient fees, and per-protocol startup stipends.
What You'll Do
- Serve as the named PI on industry-sponsored clinical trial agreements and hold site-level regulatory accountability under Form FDA 1572
- Lead all protocol activities at your site in compliance with ICH-GCP E6 R2/R3 and applicable FDA regulations (21 CFR Part 312)
- Oversee patient safety monitoring, informed consent processes, and adverse event identification and reporting
- Supervise and delegate to study coordinators via a current Delegation Log
- Maintain the site Trial Master File (TMF) in inspection-ready condition
- Serve as primary point of contact for sponsor/CRO monitoring visits, audits, and data query resolution
- Collaborate closely with the AC Group team on site startup, enrollment, and closeout
Required Qualifications — Mandatory
- Active Registered Nurse (RN) license in good standing — no lapsed or restricted licenses will be considered
- Minimum 2 years of Documented prior experience as a named Principal Investigator or Sub-Investigator on at least one industry-sponsored clinical trial — applicants without hands-on trial site experience will not be reviewed
- Current Good Clinical Practice (GCP) certification (ICH E6 R2 or R3) — must be active, current, and submitted with application
- All applicable nursing credentials and specialty certifications must be current and in good standing
Preferred Qualifications
- Phase III or Phase IV / post-marketing trial experience preferred
- ACRP Certified Clinical Research Professional (CCRP) or SOCRA CCRP credential
- Experience with EDC platforms (Medidata Rave, REDCap, Veeva Vault)
- Oncology, cardiology, neurology, or other specialty nursing background aligned with our active protocol portfolio
- Prior Form FDA 1572 signatory experience
Compensation
- FMV-based hourly rate based on specialty and experience
- Per-patient and per-visit fees per active protocol
- Site startup stipend upon protocol activation
- Flexible engagement — compatible with existing clinical roles
Apply today [email protected]
Pay: From $70.00 per hour
Application question(s):
- Do you have minimum 2 years experience as a PI?
Work Location: Hybrid remote in Canada
