British Columbia Biologist Jobs – 54 Openings This Week

Cell-Based Assay – Senior Scientist
Signalchem Biotech Inc. —Richmond, BC
- From $85,000 a year
- Full-time
- Doctoral degree
- Laboratory experience
- Master's degree
- Dental care
- Paid time off
Quick apply
Research Scientist, Assay Development
Signalchem Biotech Inc. —Richmond, BC
- From $70,000 a year
- Full-time
- Doctoral degree
- Research
- Master's degree
- Dental care
- Paid time off
Quick apply
Environmental Technician
Nupqu Resource Limited Partnership —Fernie, BC
- $25–$27 an hour
- Temporary
- Microsoft Excel
- Microsoft Outlook
- Microsoft Office
Quick apply
Fisheries Biologist
Trinity Consultants Canada —Victoria, BC
- $40–$50 an hour
- Full-time
- Hybrid work
- Quality Control
- Mentoring
- Business
Quick apply
Marine Biologist 2
HDR —Victoria, BC
- $82,000–$117,000 a year
- Full-time
- Microsoft Office
- Business development
- Bachelor's
- Disability insurance
- Dental care
Aquatic Biologist (Intermediate)
Envirochem —North Vancouver, BC
- $37–$46 an hour
- Immediate opening
- Hybrid work
- Word processing
- Writing skills
- Research
Quick apply
Genome Analyst - Division of Genome Diagnostics, Dept. of Pathology and Laboratory Medicine - BC Children’s Hospital & BC Women’s Hospital
BC Women's Hospital & Health Centre —Vancouver, BC
- $108,147–$155,461 a year
- Temporary
- Doctoral degree
- Computer Science
- Maintenance
Aquatic Biologist (Qualified Aquatic Environmental Specialist)
Canacre —Vancouver, BC
- $75,000–$105,000 a year
- Full-time
- Microsoft Office
- Budgeting
- Communication skills
- Disability insurance
- Dental care
Quick apply
Computational Biologist, Database Development- Genome Sciences Centre - Vancouver
BC Cancer —Vancouver, BC
- $40.19–$50.20 an hour
- Temporary
- Computer science
- Computer Science
- SQL
Lab Scientist - Genome Analyst
Vancouver Coastal Health —Vancouver, BC
- $46.39–$66.68 an hour
- Temporary
- Doctoral degree
- Computer literacy
- Laboratory experience
- Wellness program
- Dental care
3d
Intermediate Fisheries Biologist
True Environmental —Vancouver, BC
- $80,000–$120,000 a year
- Full-time
- Microsoft Office
- Business development
- Bachelor's
Intermediate Environmental Biologist
McElhanney Ltd. —Langley, BC
- $85,000–$120,000 a year
- Business development
- Bachelor's
- Mentoring
- Dental care
- Tuition reimbursement
Biologist - Hourly
Gitxsan Environmental Services Inc —Hazelton, BC
- Hybrid work
- Research
- Microsoft Office
- Bachelor's
Senior Research Scientist, Cell Biology - Organoid/iPSC
Applied Biological Materials Inc —Richmond, BC
- $100,000–$150,000 a year
- Contract
- Doctoral degree
- Data analysis skills
- Research
- Dental care
- Life insurance
Quick apply
Undergraduate Co-op Student – R&D Biologics Discovery
Amgen —Burnaby, BC
- $45,000–$55,000 a year
- Full-time
- Data analysis skills
- Laboratory experience
- Research
2d
Junior Biologists & Agrologists
DWB Consulting Services Ltd. —Prince George, BC
- $32–$44 an hour
- Full-time
- Writing skills
- Master's degree
- Bachelor's
Quick apply
Biologist
AtkinsRéalis —Vancouver, BC
- $68,800–$94,600 a year
- Full-time
- Hybrid work
- Research
- Bachelor's
- Mentoring
Scientist, Biomolecular Interactions (12 Month Contract)
Amgen —Burnaby, BC
- $109,254.75–$147,815.25 a year
- Contract
- Doctoral degree
- Master's degree
- Analysis skills
3d
Scientist, Immunoengineering
Aspect Biosystems —Vancouver, BC
- $90,000–$114,000 a year
- Medicine
- Doctoral degree
- Engineering
Quick apply
Research Scientist
Signalchem Biotech Inc. —Richmond, BC
- From $70,000 a year
- Full-time
- Doctoral degree
- Laboratory experience
- Research
- Dental care
- Paid time off
Quick apply

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Cell-Based Assay – Senior Scientist

Signalchem Biotech Inc.
Richmond, BC

Quick apply

Job details

Full-time
From $85,000 a year

Qualifications

Biology
Molecular Biology
Doctoral degree
Cell culture
Laboratory experience
Master's degree
Quality Control
Data analytics
Microscopy

Full job description

Company Introduction:

Founded in 2004, SignalChem Biotech is a world’s leader in the research, development, and manufacturing of active kinases and disease-relevant kinase mutants. With expertise in cellular signaling, molecular biology, and biochemistry, SignalChem has developed over 4,000 functional recombinant protein products, establishing itself as a key player in the global market for active recombinant signaling enzymes. Recently acquired by Sino Biological, a world-renowned reagent supplier and contract research organization listed on ChiNext of the Shenzhen Stock Exchange (301047 Sino Biological Inc.). SignalChem is now expanding its capabilities and creating multiple new positions.

Job Description:

We are seeking a hands-on Senior Scientist to develop, optimize, and execute cell-based functional assays for drug discovery, reagent characterization, and custom CRO programs across biologics and small molecules.

The ideal candidate has strong mammalian cell culture skills and practical experience with multiple functional assay formats. The scientist will be responsible for assay design, experimental execution, troubleshooting, quantitative data analysis, and preparation of high-quality client or internal study reports.

Key Responsibilities

1. Mammalian Cell Culture & Assay Readiness

● Cell Line Culture & Maintenance: Maintain adherent and suspension mammalian cell lines, including receptor-expressing and reporter cell lines; perform routine passaging, cryopreservation, thawing, cell counting, viability assessment, and basic culture QC.

● Primary Cell Handling: Handle primary cells such as PBMCs, whole-blood-derived cells, or other project-specific primary cell types when required; support cell isolation, stimulation, and optimization of culture conditions.

● Assay Cell Preparation & Qualification: Support transient transfection and qualification of engineered or stable cell lines, including target-expression checks, cell-health assessment, and assay-readiness testing.

2. Cell-Based Assay Development & Functional Characterization

● Functional Assays & Dose-Response Studies: Develop and execute concentration-response assays for activation, inhibition, potency, viability, proliferation, apoptosis, cytotoxicity, receptor internalization, and other cellular endpoints; determine EC50, IC50, or related parameters as appropriate.

● Reporter & Signaling Bioassays: Perform reporter- and pathway-based assays using platforms such as luciferase, SEAP, cAMP, calcium flux, beta-arrestin, or phosphorylation readouts to characterize receptor and intracellular signaling responses.

● Flow Cytometry-Based Assays: Perform flow-cytometry assays for cell-surface binding, receptor expression, internalization, apoptosis, immune-cell phenotyping, and other cellular readouts, including compensation, gating, and quantitative analysis.

● Secreted Biomarker & Cytokine Readouts: Measure cytokines, chemokines, or other secreted biomarkers using ELISA, multiplex, or compatible plate-based methods to complement cellular functional endpoints.

● Kinetic, Fluorescent & Imaging Assays: Perform fluorescence-, luminescence-, or absorbance-based kinetic assays using microplate readers and, where applicable, microscopy or imaging-based approaches.

3. Assay Optimization, Validation & Technical Support

● Assay Development & Troubleshooting: Optimize cell density, stimulation, incubation time, reagent concentrations, plate layout, controls, and detection parameters; troubleshoot assay variability and support assay transfer or scale-up when needed.

4. Data Analysis, Quality Control & Reporting

● Quantitative Data Analysis: Fit dose-response curves, calculate EC50/IC50 and percent activation/inhibition, and summarize results using software such as GraphPad Prism, FlowJo, and Excel.

● Assay Quality & Reproducibility: Monitor assay performance using controls and quality metrics such as CV, signal-to-background, dynamic range, and, where applicable, Z-prime.

● Documentation & Reporting: Maintain clear experimental records and prepare technical summaries, analyzed data packages, and raw data files for internal teams, project managers, or CRO clients.

Required Qualifications & Technical Skills

● Education: Ph.D. in Cell Biology, Molecular Biology, Biochemistry, Pharmacology, Immunology, Biomedical Sciences, or a related field with 2+ years of relevant industry experience; or M.S. with 5+ years of relevant industry or CRO laboratory experience.

● Mammalian Cell Culture: Strong hands-on experience with mammalian cell culture, including both adherent and suspension cell lines, with demonstrated ability to maintain cell quality and troubleshoot culture-related problems.

● Cell-Based Assay Experience: Demonstrated experience developing or executing multiple cell-based functional assay formats, such as reporter assays, receptor signaling assays, viability/proliferation assays, apoptosis/cytotoxicity assays, or other pharmacology-oriented cellular assays.

● Flow Cytometry: Hands-on experience with flow cytometry for cellular binding, receptor expression, phenotyping, or functional assays, including basic panel design, compensation, gating, and analysis using software such as FlowJo.

● Plate-Based Assays & Instrumentation: Proficiency with luminescence, fluorescence, and absorbance assays and multimode plate readers; experience with ELISA, HTRF/TR-FRET, or related assay technologies is a plus.

● Experimental Design & Data Analysis: Ability to design controlled experiments, analyze quantitative biological data, interpret dose-response relationships, identify sources of assay variability, and communicate conclusions clearly.

Preferred Qualifications

● Prior experience working in a CRO / Contract Research Organization, bioassay group, or fast-paced biotechnology or pharmaceutical discovery environment.

● Experience with primary cells, transient transfection, stable cell-line generation, automated liquid handling, high-content imaging, or advanced signaling assays is an advantage.

● Experience managing multiple concurrent projects and communicating experimental results to project managers, cross-functional teams, or external clients.

Job Type: Full-time

Pay: From $85,000.00 per year

Benefits:

Company events
Dental care
Extended health care
On-site parking
Paid time off
Vision care

Experience:

Cell culture: 1 year (preferred)
flow cytometry: 1 year (preferred)

Work Location: In person

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Refine Your Search

biologist jobs in british columbia

Cell-Based Assay – Senior Scientist

Research Scientist, Assay Development

Environmental Technician

Fisheries Biologist

Marine Biologist 2

Aquatic Biologist (Intermediate)

Genome Analyst - Division of Genome Diagnostics, Dept. of Pathology and Laboratory Medicine - BC Children’s Hospital & BC Women’s Hospital

Aquatic Biologist (Qualified Aquatic Environmental Specialist)

Computational Biologist, Database Development- Genome Sciences Centre - Vancouver

Lab Scientist - Genome Analyst

Intermediate Fisheries Biologist

Intermediate Environmental Biologist

Biologist - Hourly

Senior Research Scientist, Cell Biology - Organoid/iPSC

Undergraduate Co-op Student – R&D Biologics Discovery

Junior Biologists & Agrologists

Biologist

Scientist, Biomolecular Interactions (12 Month Contract)

Scientist, Immunoengineering

Research Scientist

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