vancouver, bc principal scientist Jobs – 27 Openings This Week

Principal Scientist - Toxicology
AbCellera Biologics —Vancouver, BC
- $134,000–$168,000 a year
- Full-time
- Doctoral degree
- Writing skills
- Master's degree
Principal Indigenous Engagement Specialist
WSP —Vancouver, BC
- $133,200–$195,400 a year
- Writing skills
- Leadership
11d
Principal Geomorphologist
WSP —Vancouver, BC
- $119,900–$175,800 a year
- Master's degree
- Construction
Principal Resource Geologist
WSP —Vancouver, BC
- $146,500–$212,200 a year
- Engineering
- Bachelor's
- Leadership
Senior Scientist - Target Discovery & Validation – Induced Proximity Platform (IPP)
Amgen —Burnaby, BC
- $115,503–$156,269 a year
- Doctoral degree
- Master's degree
- Organizational skills
Research Associate
University of British Columbia —Vancouver, BC
- $76,128 a year
- Weekends as needed
- Microsoft Word
- Doctoral degree
- Word processing
14d
Research Scientist 2, CMC, Analytical Chemistry
Xenon Pharmaceuticals Inc. —Vancouver, BC
- $96,000–$121,400 a year
- Full-time
- Doctoral degree
- English
- Master's degree
- Disability insurance
- Dental care
Data Scientist
University of British Columbia —Vancouver, BC
- $7,622.83–$11,886.67 a month
- Full-time
- Java
- Master's degree
- SQL
7d
Research Assistant 2, Innate Lymphoid Cell and NK Cell Engineering, Crome Lab, Terry Fox Lab - BC Cancer Vancouver
BC Cancer —Vancouver, BC
- $57,347–$75,268 a year
- Temporary
- Research
- Bachelor's
- Organizational skills
Research Associate
UBC Faculty of Forestry —Vancouver, BC
- $76,128 a year
- Weekends as needed
- Microsoft Word
- Doctoral degree
- Word processing
14d
Data Scientist
UBC Faculty of Forestry —Vancouver, BC
- $7,622.83–$11,886.67 a month
- Full-time
- Java
- Master's degree
- SQL
7d
Principal Geotechnical Engineer, Deep Foundations
WSP —Vancouver, BC
- $133,200–$195,400 a year
- Engineering
Product Designer - AI-Assisted Learning Experiences
Learn. Develop. Succeed —Vancouver, BC
- $60,000–$70,000 a year
- Full-time
- Hybrid work
- No university degree
- AI
- Communication skills
- Dental care
Quick apply
Postdoctoral Fellow (Clinical Research), Implementation & Knowledge Translation for Exercise Oncology Programs (Kristin Campbell)
University of British Columbia —Vancouver, BC
- $5,000 a month
- Full-time
- Doctoral degree
- Research
- Communication skills
Principal Researcher - Systems & Networking - Microsoft Research
Microsoft —Vancouver, BC
- $142,400–$257,500 a year
- Full-time
- Doctoral degree
- Databases
- Machine learning
Principal Engineer - Tailings & Mine Waste
WSP —Vancouver, BC
- $177,600–$257,900 a year
- Doctoral degree
- Engineering
- Master's degree
Statistical Analyst
University of British Columbia —Vancouver, BC
- $6,251–$8,986 a month
- Full-time
- Microsoft Word
- Microsoft Excel
- Microsoft Access
7d
Statistical Analyst
UBC Faculty of Forestry —Vancouver, BC
- $6,251–$8,986 a month
- Full-time
- Microsoft Word
- Microsoft Excel
- Microsoft Access
7d
Postdoctoral Fellow (Clinical Research), Implementation & Knowledge Translation for Exercise Oncology Programs (Kristin Campbell)
UBC Faculty of Forestry —Vancouver, BC
- $5,000 a month
- Full-time
- Doctoral degree
- Research
- Communication skills
AI Principal Product Manager - Technical, Amazon Customer Service
Amazon Development Centre Canada ULC —Vancouver, BC
- $157,600–$263,200 a year
- Full-time
- Customer service
- Project management
- Bachelor's
- Profit sharing
- Dental care
14d

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principal scientist jobs near vancouver, bc

Principal Scientist - Toxicology

AbCellera Biologics -
Vancouver, BC

Apply Now

Job details

Full-time
$134,000–$168,000 a year

Qualifications

Doctoral degree
Writing skills
Master's degree
Communication skills

Full job description

Each of us cares about someone who will need medicines. That’s why our vision is to repeatedly beat the odds to deliver breakthrough medicines to patients that need them. We pursue truth and scientific rigour and have the courage to work at the edge of the unknown.

We are looking for an experienced, strategically minded Principal Scientist to join our expanding Non-Clinical Safety team based in Vancouver, Canada. You will be responsible for designing, planning, monitoring, and reporting of non-GLP and GLP toxicology studies and provide nonclinical safety support for early to late stage programs.

How you might spend your days

Leading the planning, design, execution and interpretation of nonclinical toxicology programs in support of IND, CTA and BLA submissions, including general toxicity and reproductive and developmental toxicology studies, in alignment with global regulatory expectations and program strategy
Serving as the primary scientific interface with contract research organizations (CROs), providing strategic oversight during protocol development, study conduct, data interpretation, and report finalization to ensure timely, high-quality, and GLP-compliant delivery of nonclinical studies
Representing the Nonclinical Safety function as a core member of cross-functional discovery and development program teams, contributing toxicology expertise to inform candidate selection, risk assessment, and overall program advancement
Providing critical scientific assessment of toxicology data and communicating clear, actionable risk-benefit evaluations and recommendations to project teams and senior leadership, including potential implications for clinical development and regulatory strategy
Authoring and reviewing nonclinical safety sections of regulatory documents (INDs, CTAs, IBs, and BLAs), and contributing as a subject matter expert to global regulatory interactions and health authority responses
Driving the development and evolution of integrated nonclinical safety strategies across AbCellera’s therapeutic portfolio, ensuring consistency, scientific rigor, and alignment with company objectives
Maintaining scientific leadership by staying current with advances in toxicology science, methodologies, and evolving regulatory guidance, and proactively translating these insights into best practices for internal programs

We'd love to hear from you if

You bring deep expertise in GLP-compliant nonclinical toxicology, including hands-on experience with US FDA 21 CFR Part 58, and a strong working knowledge of FDA, ICH, and EMA nonclinical regulatory guidance
You have a proven track record of designing, overseeing, and interpreting non-GLP and GLP toxicology studies in support of discovery and development programs; experience with oncology and/or ADC programs is highly desirable
You hold a PhD in Toxicology or a related field, with 8+ years of relevant industry experience supporting biologics development; candidates with a MSc degree and 12+ years of directly applicable experience will also be considered
You demonstrate the ability to lead scientific discussions and influence decision-making within highly matrixed, cross-functional teams through clear, confident, and effective communication
You possess excellent scientific writing skills, with experience authoring and reviewing toxicology reports and regulatory submission documents
You exhibit strong organizational and prioritization skills, enabling effective management of multiple programs and timelines in a fast-paced environment
You apply sound scientific judgment and critical problem-solving skills to assess complex datasets, identify risks, and propose strategic solutions
You thrive in a dynamic, evolving environment, demonstrating flexibility, resilience, and a proactive approach to change
You hold DABT accreditation (highly desirable, but not required)

What we offer

AbCellera’s hiring range for this role is CAD $134,000 - $168,000 annually, commensurate with your education and job-related knowledge, skills, and experience. In addition to base salary, we offer equity, annual bonus dependent on team and company performance, and a 6% (non-match) RRSP contribution.

You will have a CAD $1,500 annual Active Lifestyle Allowance, annual vacation, professional development opportunities, and comprehensive health benefits. Scientific and technical mentorship is a priority. And you’ll find a strong sense of community and connections across AbCellera through our work, clubs, and socials.

About AbCellera

Creating medicines is the most important work we can do.

We are a clinical-stage biotechnology company focused on discovering and developing antibody-based medicines in the areas of endocrinology, women’s health, immunology, and oncology. We have built a platform for advancing antibody drug programs from target to clinic, and we are using it to build our internal pipeline.

Today, our pipeline includes two drug candidates in clinical development, two preclinical development candidates (DCs) in Investigational New Drug (IND)-enabling activities, and more than 20 active discovery programs across multiple modalities and indications.

We believe that when tenacious people share a vision and work together, they can truly have a positive impact. That’s why we hire for character and intelligence, not just for CVs or experience.

We look for people with drive and energy. People we trust. People who need to know their days are being well spent. That their work really matters. In the end, our success will be measured by the impact of our medicines.

To apply

Please submit your application through our website and refer to Job ID 23346 in your cover letter. We receive a large volume of applications and are only able to contact those who are selected for an interview. All communication from our Talent Discovery team will come from an @abcellera.com email address.

Apply Now

Refine Your Search

principal scientist jobs in vancouver, bc

Principal Scientist - Toxicology

Principal Indigenous Engagement Specialist

Principal Geomorphologist

Principal Resource Geologist

Senior Scientist - Target Discovery & Validation – Induced Proximity Platform (IPP)

Research Associate

Research Scientist 2, CMC, Analytical Chemistry

Data Scientist

Research Assistant 2, Innate Lymphoid Cell and NK Cell Engineering, Crome Lab, Terry Fox Lab - BC Cancer Vancouver

Research Associate

Data Scientist

Principal Geotechnical Engineer, Deep Foundations

Product Designer - AI-Assisted Learning Experiences

Postdoctoral Fellow (Clinical Research), Implementation & Knowledge Translation for Exercise Oncology Programs (Kristin Campbell)

Principal Researcher - Systems & Networking - Microsoft Research

Principal Engineer - Tailings & Mine Waste

Statistical Analyst

Statistical Analyst

Postdoctoral Fellow (Clinical Research), Implementation & Knowledge Translation for Exercise Oncology Programs (Kristin Campbell)

AI Principal Product Manager - Technical, Amazon Customer Service

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