Markham, On Lead python full stack data Jobs – 79 Openings This Week

Software Engineer, Machine Learning
Sitero LLC —Markham, ON
- $175,000–$200,000 a year
- Full-time
- Hybrid work
- Doctoral degree
- Computer Science
- Engineering
Quick apply
Data Architect
Infostrux Solutions Inc —Toronto, ON
- $120,000–$170,000 a year
- Remote
- Azure
- Oracle
- Java
- Flexible schedule
Observability Engineer
Accommodations Plus International —Markham, ON
- $90,000–$110,000 a year
- Weekends as needed
- Computer Science
- CAD
- DevOps
- Paid time off
- Employee assistance program
Quick apply
Engineering Lead
Codal —Toronto, ON
- $130,000–$150,000 a year
- Azure
- Computer Science
- DevOps
- Dental care
- Vision care
Quick apply
Data Architect
Infostrux Solutions —Toronto, ON
- Full-time
- Remote
- Azure
- Oracle
- Java
- Flexible schedule
Data Manager
Tata Consultancy Services —Toronto, ON
- $90,000–$110,000 a year
- Azure
- SQL
- Analysis skills
Senior Backend Engineer, Entities
EvenUp —Toronto, ON
- $184,728–$249,926 a year
- Full-time
- Hybrid work
- System design
- Java
- C++
- Designated paid holidays
- Disability insurance
Quick apply
7d
Sr. Software Development Engineer / Principal, Software Development Engineer
Workday —Toronto, ON
- $168,000–$252,000 a year
- Full-time
- Computer Science
- Engineering
- AWS
Staff Software Engineer, Full Stack
Harvey —Toronto, ON
- Full-time
- Hybrid work
- Computer science
- Engineering
- Master's degree
- Relocation assistance
Engineering Tech Lead
TTEC Digital —Toronto, ON
- Full-time
- Remote
- APIs
- AI
- Python
Quick apply
Senior DevOps Engineer
Kraft Heinz Company —Toronto, ON
- $118,600–$148,200 a year
- Azure
- DevOps
- Analysis skills
- Designated paid holidays
- Paid time off
Senior Software Developer 2, Artificial Intelligence
D2L —Toronto, ON
- $130,000–$160,000 a year
- Remote
- Computer science
- Azure
- Computer Science
- Tuition reimbursement
Quick apply
Agentic AI Platform Engineer (PL862)
Paralucent —Toronto, ON
- Full-time
- Hybrid work
- Azure
- DevOps
- Java
Quick apply
Solutions Design IT Specialist
TD Bank —Toronto, ON
- $125,000–$156,000 a year
- Full-time
- System design
- Java
- Master's degree
- Paid time off
5d
Senior Backend Engineer, AI Platform
EvenUp —Toronto, ON
- $184,728–$249,926 a year
- Full-time
- Hybrid work
- System design
- Java
- C++
- Designated paid holidays
- Disability insurance
Quick apply
Firmware Engineer, Principal
Qualcomm —Toronto, ON
- Computer science
- Doctoral degree
- Computer Science
Automation Engineering Manager
Tubi - Canada —Toronto, ON
- $150,000–$214,800 a year
- Full-time
- Hybrid work
- Computer Science
- Engineering
- Java
- Paid time off
Quick apply
Senior Software Engineer
Guidewire Software —Toronto, ON
- $108,000–$135,000 a year
- Full-time
- Hybrid work
- Computer Science
- Software troubleshooting
- Engineering
- Dental care
- Paid time off
5d
Systems Architect
HTS Engineering - Heat Transfer Solutions —Toronto, ON
- $200,000–$210,000 a year
- Full-time
- Hybrid work
- Computer science
- Azure
- Computer Science
Quick apply
Sr. Machine Learning Engineer (Perception and Tracking)
Ouster —Toronto, ON
- $162,000–$180,000 a year
- Full-time
- C++
- Machine learning
- Computer networking

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lead python full stack data jobs near markham, on

Software Engineer, Machine Learning

Sitero LLC -
Markham, ON

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Job details

Full-time
$175,000–$200,000 a year

Qualifications

TensorFlow
Doctoral degree
Computer Science
PyTorch
Engineering
Master's degree
C++
Bachelor's
Distributed systems
Software development
AI
Model evaluation
Python

Full job description

Sitero is a next-generation clinical trial solutions partner, working with more than 200 Pharmaceutical, Biotech, and Institutional Research Organizations globally. We use technology to drive safety, compliance, quality, and efficiency in research and clinical trials, helping customers bring life-changing treatments to market safer and faster.

Driven by a mission to advance clinical research through a technology-enabled delivery model, Sitero leverages a deep well of knowledge across Technology, Clinical Operations, Biosafety, and Drug Safety. We are looking for engineers who are versatile, display leadership qualities, and are enthusiastic to take on new problems across the full stack as we continue to push technology forward.

Job Title: Software Engineer, Machine Learning

Location: Ontario, Canada (Mississauga area preferred)

Why Sitero?

At Sitero, you will work on projects that have a direct impact on human health. We offer a fast-paced environment where you can switch teams and projects as our business grows. We are an equal opportunity workplace committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, or Veteran status.

About the Role

We are seeking a Software Engineer, Machine Learning to lead the development of next-generation AI technologies that power our clinical trial platforms. In this role, you will sit at the intersection of AI infrastructure, model optimization, and large-scale software engineering. You will be responsible for building scalable data pipelines for AI, optimizing model performance on hardware accelerators, and deploying state-of-the-art Large Language Models (LLMs) and Multi-Modal models that revolutionize how clinical data is processed and analyzed.

You will join a collaborative team that addresses unique problems focused on maximizing scientific and real-world impact. You will not only build AI but also embody the future of engineering by using AI to accelerate your own workflows—leveraging the very tools we build and integrate to augment software development practices.

Responsibilities

AI & ML Infrastructure: Design, develop, and deploy large-scale ML infrastructure and state-of-the-art AI solutions (e.g., LLMs, Multi-Modal models) to enhance clinical trial efficiency and safety.
Systems Architecture: Serve as a technical leader for the design of high-throughput, low-latency data pipelines and storage solutions (data loading, caching, vector stores) required for massive datasets.
AI-Augmented Engineering: Actively utilize and advocate for AI-assisted development tools (e.g., coding assistants, automated refactoring agents) to accelerate the software development lifecycle, generate boilerplate, write tests, and optimize legacy codebases.
Cross-Functional Leadership: Collaborate with clinical operations, product, and research teams to translate complex business requirements into robust engineering solutions. Establish alignment on technical strategy and influence the direction of Sitero’s AI platforms.
Mentorship: Mentor engineers across the organization, fostering best practices in distributed systems, ML engineering, and the adoption of AI-native development workflows.

Minimum Qualifications

Bachelor's degree in computer science, Engineering, or a related technical field, or equivalent practical experience.
8+ years of experience in software development with proficiency in Python, C++, or similar languages.
7+ years of experience leading technical project strategy and optimizing industry-scale ML infrastructure (model deployment, evaluation, fine-tuning).
2+ years of experience with state-of-the-art AI techniques (LLMs, RAG, Computer Vision) and frameworks (PyTorch, TensorFlow, JAX).
Demonstrated proficiency in using AI models to augment software engineering practices—specifically using LLMs for code generation, debugging, architectural design validation, and documentation.
Experience designing and scaling data infrastructure, including distributed storage systems, data lakes, or high-performance ETL frameworks.

Preferred Qualifications

Master’s degree or PhD in Computer Science, Artificial Intelligence, or related technical field.
Experience with hardware/software to co-design and optimize models for specific accelerators (GPUs, custom silicon).
Background in the Life Sciences, Pharmaceutical, or Clinical Research industries.
Familiarity with modern data storage formats (Parquet, ORC) and vector database technologies.
Proven track record of technical leadership in a complex, matrixed organization, managing cross-functional projects.

Quick apply

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lead python full stack data jobs in markham, on

Software Engineer, Machine Learning

Data Architect

Observability Engineer

Engineering Lead

Data Architect

Data Manager

Senior Backend Engineer, Entities

Sr. Software Development Engineer / Principal, Software Development Engineer

Staff Software Engineer, Full Stack

Engineering Tech Lead

Senior DevOps Engineer

Senior Software Developer 2, Artificial Intelligence

Agentic AI Platform Engineer (PL862)

Solutions Design IT Specialist

Senior Backend Engineer, AI Platform

Firmware Engineer, Principal

Automation Engineering Manager

Senior Software Engineer

Systems Architect

Sr. Machine Learning Engineer (Perception and Tracking)

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