Hamilton, On Senior specialist, quality operations Jobs – 1346 Openings This Week

Senior Specialist, Quality Operations
AstraZeneca —Hamilton, ON
- $88,296.80–$115,889.55 a year
- Temporary
- Engineering
- ERP systems
- Laboratory experience
1d
ROBOTICS FOREMAN – ELECTRICAL & AUTOMATION
NATIONAL STEEL CAR —Hamilton, ON
- $43–$48 an hour
- Overtime
- Schematics
- Supervising experience
- In-person
- Dental care
- Tuition reimbursement
Quick apply
Eddy Current Level II Technician
Applus+ —Burlington, ON
- Overtime
- Customer service
- Writing skills
- Microsoft Office
Senior Technical Service Specialist – Major Appliances
Koolatron Corporation —Brantford, ON
- $50,000–$65,000 a year
- Customer service
- Electrical experience
- In-person
Quick apply
Marine HSQE & Compliance Specialist
Mckeil Marine Limited —Burlington, ON
- Full-time
- Writing skills
- Engineering
- Microsoft Office
Quick apply
Catering Chef
Scarlett House Catering Inc. —Hamilton, ON
- $85,000–$95,000 a year
- Weekends as needed
- CPR Certification
- Microsoft Excel
- Hotel
- Dental care
- Employee assistance program
Quick apply
Director of Construction
WDI Group —Ancaster, ON
- $120,000–$150,000 a year
- Full-time
- Hybrid work
- Microsoft Excel
- PMP
- Engineering
- Mileage reimbursement
- Paid time off
Quick apply
Director of Tendering
Ontario Shipyards Inc. —Hamilton, ON
- Full-time
- Engineering
- ERP systems
- Finance
Quick apply
Landscape Maintenance Team Leader
Jeff's Outdoor —Caledonia, ON
- $1,200–$1,300 a week
- Full-time
- Supervising experience
- In-person
- Leadership
- Store discount
- Disability insurance
Quick apply
Millwright - Brantford
FERRERO —Hamilton, ON
- From $46.84 an hour
- 8 hour shift
- Schematics
- Maintenance
- High school diploma or GED
- Relocation assistance
- Dental care
Quick apply
Journeyman Millwright - Brantford
FERRERO —Hamilton, ON
- From $46.84 an hour
- 8 hour shift
- Schematics
- Maintenance
- High school diploma or GED
- Relocation assistance
- Dental care
Quick apply
Inventory and Production Coordinator
Vyn Inc —Ancaster, ON
- $25–$29 an hour
- Full-time
- Microsoft Excel
- Inventory management
- ERP systems
- Dental care
Quick apply
Development Supervisor
Thyssen Mining Construction of Canada —Ontario
- Weekends as needed
- CPR Certification
- Engineering
- Supervising experience
Quick apply
Sous Chef
Confidential —Ancaster, ON
- $24–$26 an hour
- Part-time
- Sanitation
- Cooking
- High school diploma or GED
- Paid time off
Quick apply
Afternoon Production Team Lead
Confidential —Burlington, ON
- $23–$25 an hour
- Full-time
- Team management
- In-person
- Leadership
- Dental care
- Paid time off
Quick apply
Heavy Equipment Hydraulic Technician - 3 Yrs Exp.
Bay-Lynx Manufacturing Inc. —Hamilton, ON
- $27–$32 an hour
- Full-time
- Schematics
- High school diploma or GED
- Assembly
- Wellness program
- Dental care
Quick apply
Program Manager (RECE)
Umbrella Family and Child Centres of Hamilton —Hamilton, ON
- $80,000–$95,000 a year
- Full-time
- CPR Certification
- Management
- First Aid Certification
- Employee assistance program
Quick apply
Licensed Millwright - Brantford
FERRERO —Hamilton, ON
- From $46.84 an hour
- 8 hour shift
- Schematics
- Maintenance
- High school diploma or GED
- Relocation assistance
- Dental care
Quick apply
Steamfitter
BUNGE —Hamilton, ON
- Overtime
- Heavy lifting
- Welding
- Designated paid holidays
Quality Control Coordinator (Geochemistry)
Actlabs —Ancaster, ON
- $26–$30 an hour
- Full-time
- Doctoral degree
- Laboratory experience
- English
Quick apply

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senior specialist, quality operations jobs near hamilton, on

Senior Specialist, Quality Operations

AstraZeneca -
Hamilton, ON

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Job details

Temporary | Permanent | Fixed term contract
$88,296.80–$115,889.55 a year
1 day ago

Qualifications

Power BI
Engineering
ERP systems
Laboratory experience
Laboratory information management systems
Quality management
Microsoft Office
Bachelor's
Pharmacy
Manufacturing

Full job description

Location Hamilton, Ontario, Canada Job ID R-254036 Date posted 07/06/2026

Job Title: Senior Specialist, Quality Operations

Location: Hamilton, Ontario

Onsite 5 days/week

Fusion Pharmaceuticals, a member of the AstraZeneca Group, is a clinical-stage oncology company focused on developing next generation radio conjugates (RCs) as precision medicines. Fusion has multiple pipeline programs entering early FIH trials. In addition, Fusion is pursuing combination programs between RCs and other therapeutic modalities including DNA Damage Response Inhibitors (DDRis) and immune-oncology agents. To support execution for these programs, Fusion has a fully operational Good Manufacturing Practice (GMP) compliant, brand new radio conjugate manufacturing facility to meet the demand for our growing pipeline of RCs.

Position Summary

The Senior Specialist, Quality Operations ensures day-to-day quality oversight of manufacturing, packaging, testing, and distribution activities. The role executes quality system processes, provides on-the-floor support, and drives robust investigations and CAPA to protect product quality, patient safety, and regulatory compliance. This position partners closely with Operations, QC, Supply Chain, Engineering, and Regulatory to maintain right-first-time execution and continuous improvement. This position reports to AD, Quality Operations.

Key Responsibilities

Provide on-the-floor QA presence for manufacturing and packaging; verify adherence to procedures, critical parameters, and line clearance; support start-up, interventions, and batch record execution.
Lead or facilitate timely investigations using root cause tools (5-Why, Ishikawa, FMEA); define corrective/preventive actions; perform effectiveness checks; trend issues and drive systemic fixes.
Author, assess, and approve changes to processes, equipment, materials, and documentation; ensure risk assessments and validation impacts are addressed.
Operate QMS elements including SOPs, training, complaints, supplier quality, stability, APR/PQR inputs, and metrics; ensure records are complete and audit ready.
Oversee aseptic behaviors, gowning, environmental monitoring, sterilization and media fill readiness; review EM trends and investigate excursions.
Coordinate with QC for testing review, OOS/OOT investigations, method or instrument changes, and data integrity checks.
Support incoming material release, sampling plans, and supplier notifications; participate in supplier qualifications and audits as needed.
Prepare areas and documentation for internal/external audits; host tours, answer inquiries, and manage observation responses; ensure sustained readiness.
Deliver or reinforce GMP and SOP training; coach operators on quality expectations; promote a right-first-time culture.
Analyze defects and deviation trends; implement standard work, mistake-proofing, and process capability improvements; contribute to quality KPIs and dashboards.
Ensure ALCOA+ principles in all records; review electronic systems for permissions, audit trails, and validated state; enforce good documentation practices.
Support tech transfers, scale-up, equipment qualification, and validation activities; provide quality input to project teams.

Qualifications

Bachelor’s degree in life sciences, engineering, pharmacy, or related field; advanced degree is a plus.
4–7+ years in quality operations within manufacturing or laboratory environments; experience in regulated industries preferred.
Strong knowledge of QMS, deviations/CAPA, change control, batch record review, and audit/inspection processes; familiarity with validation, data integrity, and statistical trending tools; proficiency with electronic QMS/LIMS/ERP and MS Office/Power BI.
Experience in an aseptic GMP manufacturing environment is an asset
Knowledge of FDA 21 CFR 210/211, EU GMP/Annexes, ICH Q9/Q10, PIC/S.
Detail orientation, problem-solving, clear communication, ability to influence without authority, collaboration, and resilience under time pressure.
>5% travel required.

Great People want to Work with us! Find out why:

GTAA Top Employer Award for 11 years
Top 100 Employers Award
Canada’s Most Admired Corporate Culture
Learn more about working with us in Canada
View our YouTube channel

Are you interested in working at AZ, apply today!

AstraZeneca is an equal opportunity employer that is committed to diversity and inclusion and providing a workplace that is free from discrimination. AstraZeneca is committed to accommodating persons with disabilities. Such accommodation is available on request in respect of all aspects of the recruitment, assessment and selection process and may be requested by emailing [email protected].

⠀

Annual base salary for this position ranges from 88,296.80 to 115,889.55.

AstraZeneca is committed to providing fair and equitable compensation opportunities to all colleagues. Our compensation policies and practices have been designed to allow colleagues to progress through the salary range over time as they progress in their role. The range provided in this posting represents an offer pay range used in a majority of situations. The base pay offered will vary depending on multiple individualized factors, including the candidate's skills and experience, job-related knowledge, and other specific business and organizational needs. In some cases, offers outside the range may also be considered to address unique circumstances.

In addition, our permanent positions offer an annual Variable Pay Bonus/Short Term Incentive opportunity as well as eligibility to participate in our equity-based long-term incentive program (if applicable to role). Benefits offered for permanent roles include a competitive Flex Benefits & Retirement Savings Program, 4 weeks’ paid vacation, and annual Personal Days. Fixed Term Contract/Temporary positions (excluding students) are offered a Contract Benefits Program.

We are using AI as part of the recruitment process.

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Refine Your Search

senior specialist, quality operations jobs in hamilton, on

Senior Specialist, Quality Operations

ROBOTICS FOREMAN – ELECTRICAL & AUTOMATION

Eddy Current Level II Technician

Senior Technical Service Specialist – Major Appliances

Marine HSQE & Compliance Specialist

Catering Chef

Director of Construction

Director of Tendering

Landscape Maintenance Team Leader

Millwright - Brantford

Journeyman Millwright - Brantford

Inventory and Production Coordinator

Development Supervisor

Sous Chef

Afternoon Production Team Lead

Heavy Equipment Hydraulic Technician - 3 Yrs Exp.

Program Manager (RECE)

Licensed Millwright - Brantford

Steamfitter

Quality Control Coordinator (Geochemistry)

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